Conference / Meeting

Maria Soledad Sosa

Icahn School of Medicine at Mount Sinai, Department of Pharmacological Sciences - Laboratory of Cancer Metastasis -New York NY
8 July 2021
Start time 
4:00 pm
Polo Ferrari 2 - Via Sommarive 9, Povo (Trento)
via zoom
Dipartimento di Biologia Cellulare, Computazionale e Integrata - CIBIO
Target audience: 
University community
Contact person: 
Department of Cellular, Computational and Integrative Biology - CIBIO
Contact details:

Elucidating the biology of minimal residual disease

Metastasis remains the main cause of human cancer deaths. It has been proposed that disseminated tumor cells (DTCs) are the source for metastasis in several tumor types and that they remain in a reversible
dormant state for prolonged periods of time resisting treatments until, eventually, they will reactivate and form metastasis. Therefore, it is of utmost importance to better understand the mechanisms driving DTC
dormancy and reactivation in order to extend remission and prevent relapse.In this talk, I will present data on dormancy programs, mechanisms of reactivation and potential therapeutic strategies to extend remission phase.

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