Non-coding RNAs as emerging biomarkers for human diseases:

The plethora of RNA species in the living world shows that between DNA and protein, the regulation of life has almost limitless potential. In this workshop, we will try to cast light on recent advances in non-coding RNAs used as biomarkers for human diseases and the difficulty of translating them into clinics.

AGENDA

Morning

8.30-9.00 Arrival and registration

9.00 - 9.15 Welcome and Introduction: Paolo Macchi - Director CIBIO, Michela Alessandra Denti (CIBIO), Cristina Ress (OPTOI)

9.15 - 9.30 Salvatore Pernagallo (DestiNA Genomica, Granada, Spain) The diaRNAgnosis project

9.30 - 10.30 Keynote lecture: Leendert Looijenga (Princes Màxima Center for pediatric oncology, Utrecht, the Netherlands) 
MicroRNA-371-3 as unique liquid biopsy biomarker for malignant germ cell tumors

10.30 - 11.00 Coffee break

11.00 - 11.30 Cinzia Di Pietro (Department of Biomedical and Biotechnological Sciences, Section of Biology and Genetics “G. Sichel”, University of Catania, Italy) 
Blastocoel Fluid microRNAs: from biological function to biomedical application

SHORT TALKS
11.30 Leonardo Ricci (Department of Physics, University of Trento)
Confidence, significance, p-values: how much trust do biomarkers deserve?

11.45 Lucia La Sala (IRCCS MultiMedica - Polo Scientifico Tecnologico Milano, IT)
MiR-21 as novel strategy for screening of hyperglycemia-induced damage

12.00 Vito D’Agostino (Laboratory of Biotechnology and nanomedicine, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento)
Interfering with hnRNPA2B1-RNA interaction to modulate RNA sorting in extracellular vesicles

12.15- 12.45 Juan Diaz Mochon (NanochemBio lab, Genyo research centre, Department of Medicinal and Organic Chemistry, University of Granada, Spain) Chemical probes for detecting nucleic acids for molecular diagnostic

Afternoon

12.45 - 14.30 Lunch and posters

SHORT TALKS

14.30 Zein Mersini Besharat (Sapienza University of Rome, Rome, Italy)
Circulating microRNAs as biomarkers in Medullary Thyroid Carcinoma patients

14.45 Ilaria Grossi (Department of Molecular and Translational Medicine, Division of Biology and Genetics, University of Brescia)
MiR-193a-3p and miR-23b-3p in human hepatocellular carcinoma: from biological function to potential biomedical application

15.00 Davide Barbagallo (Dept. BIOMETEC, UniCT, Via S. Sofia, 89, Catania)
The emerging roles of circSMARCA5 in glioblastoma

15.15 Miguel Pellegrini (NeuroEpigenetics Laboratory, Department of Cellular, Computational and Integrative Biology, University of Trento)
Circular RNAs as potential biomarkers in Huntington's disease pathogenesis 

15.30 -16.00 Marco Ragusa (Department of Biomedical and Biotechnological Sciences, Section of Biology and Genetics “G. Sichel”, University of Catania, Italy) 
Non Coding RNAs in Uveal Melanoma

16.00 -16.30 Michela A. Denti (Department of Cellular, Computational and Integrative Biology, University of Trento) 
Circulating microRNAs as biomarkers in neurodegenerative diseases

16.30 - 17.00 Coffee break

17.00 - 18.00 ROUND TABLE: Translating RNA biomarkers to the clinics
Moderator Davide Ederle (Hub Innovazione Trentino, Trento, Italy)
Cristina Ress, Salvatore Pernagallo, Leendert Looijenga, Michela A. Denti

18.00 - 18.30 Poster Prizes and final remarks

Organizing committee:

Michela A. Denti (CIBIO), Simone Detassis (OPTOI), Cristina Ress (Optoi), Salvatore Pernagallo (Destina Genomica)

Supporters:

Patronized by: