Conference / Meeting

Structural characterisation of EDEM:PDI, the glycoprotein folding ERAD checkpoint

Pietro Roversi
11 April 2024
Start time 
5:00 pm
Polo Ferrari 1 - Via Sommarive 5, Povo (Trento)
Room A206
Organizer: 
Department of Cellular, Computational and Integrative Biology - CIBIO
Target audience: 
University community
Attendance: 
Free
Contact person: 
Department of Cellular, Computational and Integrative Biology - CIBIO
Contact details: 
comunicazione.cibio@unitn.it

The first structure of the checkpoint of Endoplasmic Reticulum Associated Degradation (ERAD) suggests the PDI recruits misfolded glycoprotein clients to the mannosidase via transient disulfide bonds.

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