Conference / Meeting

Telomeres and cancer: Tumor Suppression and Genome Instability

Dr. Titia de Lange - Pezcoller Lectures
10 May 2024
Start time 
2:30 pm
Fondazione Bruno Kessler
Sala Stringa
Department of Cellular, Computational and Integrative Biology & Pezcoller Foundation
Target audience: 
University community
Contact person: 
Department of Cellular, Computational and Integrative Biology - CIBIO
Contact details:

Winner of the 2024 Pezcoller Foundation - AACR Award for Extraordinary Achievement in Cancer Research


De Lange is being recognized for discovering the molecular mechanisms by which telomeres protect chromosome ends, characterizing the function of the shelterin protein complex, and demonstrating how loss of telomere protection results in aberrant genomic integrity and tumorigenesis.

De Lange’s research has brilliantly elucidated the role of telomeres—regions of repetitive nucleotide sequences at the ends of chromosomes—in cancer onset and progression, mainly through work that has defined the role of the shelterin protein complex in protecting telomeric DNA by blocking DNA damage and repair activity.

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