Seminar

Fetal canalization of BM preference

Double-dissociation of pathogenesis by VPA and nAChR blockade and recovery by bumetanide, inhibitor of chloride cotransporter
22 June 2022
Start time 
5:30 pm
Ex Manifattura - Piazza della Manifattura 1, Rovereto
ACN Lab - Seminar Room, 2nd floor, Building n. 14
Organizer: 
ACN Lab
Target audience: 
Everyone
Attendance: 
Free
Online
Contact details: 
grazia.gambardella@unitn.it
Speaker: 
Toshiya Matsushima - Professor Emeritus, Faculty of Science, Hokkaido University, Japan

Biological motion preference (BM) appears spontaneously in neonatal domestic chicks as well as human newborns. The chick’s BM is induced by imprinting, which expands the sensitive period and subsequently canalizes the social attachment to biological objects via thyroid hormone action. Beside the sodium valproate (VPA) effect, we report another molecular process, namely BM impairment by fetal blockade of nAChR including those by neonicotinoid. Distinct paths of pathogenesis could converge onto a common ASD-like behavioral phenotype.

Host: Giorgio Vallortigara

It is possible to connect to the event via ZOOM, to request the link and passcode write to Grazia Gambardella