Seminar
The role of negr1 in neuronal morphology and connectivity
4 February 2022
Start time
11:00 am
Polo Ferrari 1 - Via Sommarive 5, Povo (Trento)
Aula A221
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Organizer:
Dipartimento di Fisica
Target audience:
University community
Attendance:
Free
Contact person:
prof. Lorenzo Pavesi
Contact details:
segreteria del Dipartimento di Fisica
Speaker:
Francesca Pischedda
Department of Physics (Nanoscience Laboratory)
Abstract:
I characterized the role of Negr1, a novel IglON family adhesion protein, in neuronal development. More in the specific using biochemistry, microscopy and in utero electroporation techniques I demonstrated that the misregulation of Negr1 impairs both neuronal morphology and neuronal migration during brain development, leading to connectivity defects observed in neuropsychiatric diseases such as Autism.
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