DNA damage response in ageing and cancer and the role of non coding RNAs

14 ottobre 2016
Versione stampabile

Venue: Edificio Povo 2, via Sommarive nr. 9, Povo (Tn) - Room B107
 At 2:00 p.m.

  • Fabrizio d'Adda di Fagagna - IFOM - The FIRC Institute of Molecular Oncology, Milano - IGM (Istituto di Genetica Molecolare) - CNR (Consiglio Nazionale delle Ricerche)

DNA damage and ensuing DNA damage response (DDR) activation are key players in tumor suppression and ageing. I will discuss how DDR impacts on them and on the biology of stem cells. I will also describe a novel key role for non-coding RNAs in the modulation of the DNA damage response and how this allows us an unprecedented control on DDR events.