Mutations in SRSF2 Identified in Myelodysplasia affect RNA Binding Affinity, Specificity, and Splicing

18th March 2015

Versione stampabile

Venue: Edificio Povo 1, via Sommarive nr. 5, Povo (Tn) - Room A108
 at 2:00 p.m.

  • Stephanie Halene -  Yale Medical School,  New Haven, CT, USA

Dr. Halene's laboratory studies hematopoiesis and myelopoiesis and in particular how abnormalities of the hematopoietic stem and progenitor cells lead to diseases with abnormal numbers and function of blood cells. The laboratory uses primary patient cells and murine models to study mechanisms of disease leading to myelodysplasia and acute myeloid leukemia with the ultimate goal to contribute to the development of novel treatments.