Seminario
The role of negr1 in neuronal morphology and connectivity
4 febbraio 2022
Orario di inizio
10:00
Polo Ferrari 1 - Via Sommarive 5, Povo (Trento)
Aula A221
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Organizzato da:
Dipartimento di Fisica
Destinatari:
Comunità universitaria
Partecipazione:
Ingresso libero
Referente:
prof. Lorenzo Pavesi
Contatti:
segreteria del Dipartimento di Fisica
Speaker:
Francesca Pischedda, Department of Physics (Nanoscience Laboratory)
Abstract
I characterized the role of Negr1, a novel IglON family adhesion protein, in neuronal development. More in the specific using biochemistry, microscopy and in utero electroporation techniques I demonstrated that the misregulation of Negr1 impairs both neuronal morphology and neuronal migration during brain development, leading to connectivity defects observed in neuropsychiatric diseases such as Autism.
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