Fetal canalization of BM preference
Biological motion preference (BM) appears spontaneously in neonatal domestic chicks as well as human newborns. The chick’s BM is induced by imprinting, which expands the sensitive period and subsequently canalizes the social attachment to biological objects via thyroid hormone action. Beside the sodium valproate (VPA) effect, we report another molecular process, namely BM impairment by fetal blockade of nAChR including those by neonicotinoid. Distinct paths of pathogenesis could converge onto a common ASD-like behavioral phenotype.
Host: Giorgio Vallortigara
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